Aim 1. Expand the previously developed intervention components at the three participating CTSA hubs using community-engaged approaches: (1) Storytelling for promotion of research literacy, (2) Simulation-based training for improving culturally appropriate recruitment and informed consent, and (3) e-Consent. Iterative pilot testing will refine the intervention and ensure compatibility with routine clinical trial work flow.
Aim 2. Test the effectiveness of the STRIDE intervention to improve participation of African Americans and Latinos in ongoing translational clinical trials at each of our three partnering CTSA hubs. Effectiveness will be assessed with a randomized interrupted time series design with contemporary controls and the primary outcome will be enrollment of African American and Latino participants.
Aim 3. Promote widespread translation/dissemination to CTSA hubs, other research institutions and community organizations. We will develop an integrated toolkit and make it publically available on the Internet, actively engage the entire CTSA network and offer a series of workshops at national venues.